{"id":6526,"date":"2023-08-22T12:40:00","date_gmt":"2023-08-22T11:40:00","guid":{"rendered":"https:\/\/the7.io\/cbd\/?p=6526"},"modified":"2024-11-26T17:24:58","modified_gmt":"2024-11-26T16:24:58","slug":"sto-je-endokanabinoidni-sustav","status":"publish","type":"post","link":"https:\/\/calishop.net\/en\/2023\/08\/22\/sto-je-endokanabinoidni-sustav\/","title":{"rendered":"\u0160to je endokanabinoidni sustav?"},"content":{"rendered":"
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Endokanabinoidni sustav (ECS)<\/strong> unutarnji je sustav tijela koji se bavi regulacijom razli\u010ditih funkcija, uklju\u010duju\u0107i apetit, spavanje, bol, imunitet i reprodukciju te brojne druge procese.<\/div>

\u00a0<\/h2>

ECS se sastoji od:<\/strong><\/h2>
\u00a0<\/div>
\u00a0 \u00a0 \u00a01. ENDOKANABINOIDA,<\/strong><\/div>
\u00a0 \u00a0 \u00a02. KANBINOIDNIH RECEPTORA,<\/strong> kojih u ljudskom tijelu ima preko 20, a od kojih su najva\u017eniji CB1, CB2, TRPV1, GPR18, GPR55, GPR119 koji se nalaze na stanicama u tijelu.<\/div>
\u00a0 \u00a0 \u00a03. ENZIMA<\/strong>\u00a0koji proizvode i razgra\u0111uju endokanabinode.<\/div>
\u00a0<\/div>

ENDOKANABINOIDI<\/strong><\/h3>
Endokanabinoidi su glasnici u endokanabinoidnom sustavu. To su molekule proizvedene u va\u0161im \u017eiv\u010danim stanicama, a njihova je primarna svrha slanje razli\u010ditih poruka razli\u010ditim dijelovima tijela kako bi se zadovoljile njegove \u017eelje i potrebe. Najva\u017eniji endokanabinoidi su anandamid i 2-arachidonoilglicerol.<\/div>
\u00a0<\/div>

KANABINOIDNI RECEPTORI<\/strong><\/h3>
Nije, naravno, dovoljno samo poslati poruku \u2013 potrebno ju je i primiti, razumjeti i implementirati. A to je posao kanabinoidnih receptora . Ljudi imaju vi\u0161e od 20 razli\u010ditih tipova kanabinoidnih receptora, ali CB1 i CB2 receptori su najpoznatiji i mogu\u0107e ih je u ljudskom tijelu na\u0107i u izobilju. Primarna uloga kanabinoidnih receptora je mijenjanje intenziteta razli\u010ditih procesa u tijelu. Vrsta procesa ovisi o tome koji se receptor koristi i gdje se nalazi. Va\u0161 je mozak, na primjer, pun CB1 receptora. Ti su receptori tako\u0111er raspore\u0111eni po va\u0161em \u017eiv\u010danom sustavu te igraju zna\u010dajnu ulogu u funkcijama kao \u0161to su kretanje, razmi\u0161ljanje, pam\u0107enje i bol. CB2 receptori, s druge strane, mogu\u0107e je prona\u0107i u dijelovima tijela odgovornima za razli\u010dite imunolo\u0161ke reakcije. Ve\u0107ina dijelova tijela imat \u0107e mje\u0161avinu razli\u010ditih receptora, ali neki mogu imati vi\u0161e jednih nego drugih.<\/div>
Kanabinoidne je receptore mogu\u0107e prona\u0107i u va\u0161im plu\u0107ima, jetri, srcu, ko\u017ei i mnogim drugim mjestima o kojima niti ne razmi\u0161ljate dok ne prestanu ispravno raditi. Postoje dva glavna receptora u ECS-u: CB1 receptori, koji se nalaze uglavnom u sredi\u0161njem nervnom sustavu i CB2 receptori, koji se uglavnom nalaze u imunolo\u0161kom sustavu. Endokannabinoidi, poput anandamida i 2-arachidonoilglicerola, ve\u017eu se za ove receptore i reguliraju funkcije povezane s njima.<\/div>
\u00a0<\/div>

ENZIMI<\/strong><\/h3>
Uloga enzima u endokanabinoidnom sustavu je jasna. Kada endokanabinoid zavr\u0161i sa svojim poslom slanja poruke pravom primatelju, enzimi se uklju\u010duju i rastvaraju ga, osiguravaju\u0107i da sigurno napusti na\u0161e tijelo. Enzimi tako\u0111er dopu\u0161taju na\u0161im receptorima da se vrate u svoje izvorno stanje, omogu\u0107uju\u0107i novom endokanabinoidu da se pri\u010dvrsti na receptor i do\u0111e do nove poruke.<\/div><\/div>
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Mehanizam djelovanja endokanabinoidnog sustava<\/strong><\/h2>
\u00a0<\/div>
\u00a0 \u00a0 \u00a0ECS igra va\u017enu ulogu u odr\u017eavanju homeostaze tijela, \u0161to zna\u010di da poma\u017ee u odr\u017eavanju optimalnog stanja tijela. Nedostatak endokanabinoida ili poreme\u0107aj u radu ECS-a mo\u017ee dovesti do razli\u010ditih zdravstvenih problema, uklju\u010duju\u0107i depresiju, anksioznost, bolove u mi\u0161i\u0107ima i zglobovima, probleme s probavom, probleme s apetitom te niz drugih zdravstvenih poreme\u0107aja.<\/div>
\u00a0 \u00a0 \u00a0Zdrav ECS radi neprekidno i besprijekorno. Prvo, poruke se \u0161alju putem endokanabinoida svaki put kada va\u0161e tijelo primijeti da se odre\u0111eni procesi trebaju prilagoditi. Nakon toga endokanabinoidi pronalaze prave receptore i ve\u017eu se za njih. Ovo djelovanje prenosi relevantne informacije kanabinoidnim receptorima i omogu\u0107uje im da djeluju prema primljenim informacijama. Nakon \u0161to su poruke primljene jasno i glasno, enzimi dolaze o\u010distiti mjesto i ukloniti endokanabinoide koji su upravo ispunili svoju du\u017enost i ulogu. Ovaj proces slanja poruke, njezinog prevo\u0111enja i djelovanja po njoj, odvija se stalno i kontinuirano. Naravno, taj je proces mnogo vi\u0161e od ukratko opisanog te je daleko nijansiraniji, ali za one koji nisu znanstvenici ili neurobiolozi, ovo je dovoljno znanja za shva\u0107anje va\u017enosti ECS-a.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t
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Suspendisse potenti! Ut elit tellus ipsum dolor lorem ipsum sit amet, consectetur adipiscing elit.\u00a0<\/p>","protected":false},"author":1,"featured_media":8591,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[16],"tags":[],"class_list":["post-6526","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"\n\u0160to je endokanabinoidni sustav? - CALI<\/title>\n<meta name=\"description\" content=\"Endokanabinoidni sustav (ECS) unutarnji je sustav tijela koji se bavi regulacijom razli\u010ditih funkcija, uklju\u010duju\u0107i apetit, spavanje, bol, imunitet i reprodukciju te brojne druge procese.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0160to je endokanabinoidni sustav? 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